• Trans-acting siRNA (abbreviated "ta-siRNA" or "tasiRNA") are a class of small interfering RNA (siRNA) that repress gene expression through post-transcriptional...
    9 KB (1,153 words) - 05:22, 31 January 2024
  • Vazquez F, Vaucheret H (2004). "Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs". Mol. Cell. 16 (1): 69–79. doi:10.1016/j...
    20 KB (1,022 words) - 13:20, 22 February 2024
  • Trans-regulatory elements (TRE) are DNA sequences encoding upstream regulators (ie. trans-acting factors), which may modify or regulate the expression...
    12 KB (1,301 words) - 05:51, 22 February 2024
  • Thumbnail for RNA interference
    ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
    141 KB (15,445 words) - 08:44, 6 May 2024
  • Thumbnail for Dicer
    Dicer (category RNA interference)
    immunity and defense. DCL3 generates siRNA which aids in chromatin modification and DCL4 is involved in trans-acting siRNA metabolism and transcript silencing...
    25 KB (3,276 words) - 06:00, 14 March 2024
  • Thumbnail for DCL1
    participate, such Trans-acting siRNA biogenesis. DCL1 is localized exclusively in the plant cell nucleus, together with the double-stranded RNA binding protein...
    9 KB (915 words) - 21:38, 2 December 2023
  • Thumbnail for Messenger RNA
    the RNA-induced silencing complex or RISC. This complex contains an endonuclease that cleaves perfectly complementary messages to which the siRNA binds...
    49 KB (5,922 words) - 19:29, 4 May 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    64 KB (7,522 words) - 07:46, 20 April 2024
  • Thumbnail for Non-coding RNA
    RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
    67 KB (7,214 words) - 06:02, 26 February 2024
  • MY, Poethig RS (September 2005). "A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis". Genes & Development. 19 (18): 2164–75. doi:10.1101/gad...
    57 KB (7,095 words) - 12:54, 22 February 2024
  • Thumbnail for RNA splicing
    splicing of pre-mRNA transcripts is regulated by a system of trans-acting proteins (activators and repressors) that bind to cis-acting sites or "elements"...
    37 KB (4,480 words) - 08:47, 24 February 2024
  • Thumbnail for Long non-coding RNA
    ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)...
    114 KB (12,398 words) - 22:18, 26 April 2024
  • Thumbnail for James C. Carrington
    Gustafson, Adam M.; Carrington, James C. (2005). "MicroRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants". Cell. 121 (2): 207–221. doi:10...
    8 KB (654 words) - 01:54, 3 December 2023
  • Thumbnail for Alternative splicing
    are two major types of cis-acting RNA sequence elements present in pre-mRNAs and they have corresponding trans-acting RNA-binding proteins. Splicing silencers...
    68 KB (8,378 words) - 07:49, 29 April 2024
  • Thumbnail for RNA editing
    disrupts and destabilizes the dsRNA base pairing, therefore rendering that particular dsRNA less able to produce siRNA, which interferes with the RNAi...
    61 KB (7,435 words) - 08:04, 31 March 2024
  • tissue types but the majority of trans eQTLs are tissue-dependent (dynamic). eQTLs may act in cis (locally) or trans (at a distance) to a gene. The abundance...
    14 KB (1,460 words) - 00:27, 7 October 2023
  • Z, Gustafson AM, Carrington JC (April 2005). "microRNA-directed phasing during trans-acting siRNA biogenesis in plants". Cell. 121 (2): 207–21. doi:10...
    12 KB (1,387 words) - 01:35, 4 December 2023
  • Thumbnail for DCL2
    DCL2 (category RNA interference)
    strands of dsRNA. DCL2 plays an essential role in transitive silencing of transgenes by processing secondary siRNAs, including trans-acting siRNA. To do so...
    7 KB (815 words) - 07:57, 17 April 2023
  • small interfering RNA (siRNA) small nuclear RNA (snRNA) small nucleolar RNA (snoRNA) small temporal RNA (stRNA) A subclass of microRNAs, originally described...
    251 KB (21,681 words) - 21:29, 26 April 2024
  • Thumbnail for Eukaryotic transcription
    regulated by cis-acting elements (enhancers, silencers, isolators) within the regulatory regions of the DNA, and sequence-specific trans-acting factors that...
    49 KB (5,861 words) - 08:35, 6 December 2023
  • Thumbnail for ADAR
    double-stranded RNA-specific adenosine deaminase enzyme family are encoded by the ADAR family genes. ADAR stands for adenosine deaminase acting on RNA. This article...
    38 KB (4,802 words) - 18:44, 25 April 2024
  • Cis-acting regulatory elements Trans-acting regulatory factors Gene rearrangements and amplifications Small non-coding RNA (e.g., siRNA, microRNA) G....
    9 KB (835 words) - 12:38, 29 July 2023
  • nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and...
    31 KB (3,791 words) - 13:33, 9 January 2024
  • the mRNA until the start codon. The ribosome can localize to the start site by direct binding, initiation factors, and/or ITAFs (IRES trans-acting factors)...
    15 KB (1,857 words) - 12:07, 25 December 2023
  • Thumbnail for U7 small nuclear RNA
    (1989). "In vivo and in vitro expression of U7 snRNA genes: cis- and trans-acting elements required for RNA polymerase II-directed transcription". EMBO J...
    30 KB (3,628 words) - 21:55, 5 January 2024
  • Thumbnail for RNA-directed DNA methylation
    2019). "Reaction Mechanisms of Pol IV, RDR2, and DCL3 Drive RNA Channeling in the siRNA-Directed DNA Methylation Pathway". Molecular Cell. 75 (3): 576–589...
    139 KB (14,860 words) - 07:15, 22 April 2024
  • Thumbnail for Vectors in gene therapy
    Another uses small molecules of RNA called siRNA to signal the cell to cleave specific unique sequences in the mRNA transcript of the faulty gene, disrupting...
    36 KB (4,918 words) - 09:36, 27 February 2024
  • occurring RNA such as siRNA function by this principle, making them potent gene silencers in various gene regulation mechanisms. Synthetic antisense RNA has...
    259 KB (23,542 words) - 04:59, 5 May 2024
  • Miller, W. Allen (March 15, 2004). "cis and trans Requirements for Rolling Circle Replication of a Satellite RNA". Journal of Virology. 78 (6): 3072–3082...
    23 KB (2,615 words) - 15:01, 24 January 2024
  • Thumbnail for Telomeric repeat–containing RNA
    transcribed, acting in cis, or whether they may move from one telomere to another by some unknown mechanism to regulate their functions (acting in trans). While...
    35 KB (4,668 words) - 11:25, 11 February 2024