Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid...

Tryptophan repressor (or trp repressor) is a transcription factor involved in controlling amino acid metabolism. It has been best studied in Escherichia...

bacteria. The operon is regulated so that, when tryptophan is present in the environment, the genes for tryptophan synthesis are repressed. The trp operon contains...

In addition, tryptophan is a relatively rare amino acid; many proteins contain only one or a few tryptophan residues. Therefore, tryptophan fluorescence...

Tryptophan synthase or tryptophan synthetase is an enzyme (EC 4.2.1.20) that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly...

ingestion of the dietary supplement L-tryptophan. The risk of developing EMS increases with larger doses of tryptophan and increasing age. Some research suggests...

5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent...

In enzymology, tryptophan 2,3-dioxygenase (EC 1.13.11.11) is a heme enzyme that catalyzes the oxidation of L-tryptophan (L-Trp) to N-formyl-L-kynurenine...

In enzymology, a tryptophan transaminase (EC 2.6.1.27) is an enzyme that catalyzes the chemical reaction L-tryptophan + 2-oxoglutarate ⇌ {\displaystyle...

L-Tryptophan decarboxylase (EC 4.1.1.105) is an enzyme distinguished by the substrate L-tryptophan. This enzyme catalyzes the reaction of L-tryptophan to...

Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the monoamine neurotransmitter serotonin. Tyrosine hydroxylase, phenylalanine...

Tryptophan pyrrolase may refer to: Tryptophan 2,3-dioxygenase, an enzyme Indoleamine 2,3-dioxygenase, an enzyme This set index page lists enzyme articles...

In enzymology, a tryptophan dehydrogenase (EC 1.4.1.19) is an enzyme that catalyzes the chemical reaction L-tryptophan + NAD(P)+ + H2O ⇌ {\displaystyle...

Acute tryptophan depletion (ATD) is a technique used extensively to study the effect of low serotonin in the brain. This experimental approach reduces...

enzymology, a tryptophan dimethylallyltransferase (EC 2.5.1.34) is an enzyme that catalyzes the chemical reaction dimethylallyl diphosphate + L-tryptophan ⇌ {\displaystyle...

Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. TPH1 was first discovered to support...

or placenta. In humans is encoded by the IDO1 gene. IDO is involved in tryptophan metabolism. It is one of three enzymes that catalyze the first and rate-limiting...

Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. Secondary pellagra is due to a poor ability to use the niacin within...

but not uptake of tryptophan. This lowers the ratio of these branched-chain amino acids in the bloodstream relative to tryptophan (an aromatic amino...

In enzymology, a tryptophan 2'-dioxygenase (EC 1.13.99.3) is an enzyme that catalyzes the chemical reaction L-tryptophan + O 2 + H+ ⇌ {\displaystyle \rightleftharpoons...

enzymology, a D-tryptophan N-acetyltransferase (EC 2.3.1.34) is an enzyme that catalyzes the chemical reaction acetyl-CoA + D-tryptophan ⇌ {\displaystyle...

Indoles are widely distributed in nature, most notably as amino acid tryptophan and neurotransmitter serotonin. Indole is a solid at room temperature...

Tryptophan N-monooxygenase (EC 1.14.13.125, tryptophan N-hydroxylase, CYP79B1, CYP79B2, CYP79B3) is an enzyme with systematic name L-tryptophan,NADPH:oxygen...

Tryptophan synthase (indole-salvaging) (EC 4.2.1.122, tryptophan synthase beta2) is an enzyme with systematic name L-serine hydro-lyase (adding indole...

hypercalcemia. It is caused by a defect in tryptophan absorption. Bacterial degradation of unabsorbed tryptophan in the intestine leads to excessive indole...

enzymology, a D-tryptophan N-malonyltransferase (EC 2.3.1.112) is an enzyme that catalyzes the chemical reaction malonyl-CoA + D-tryptophan ⇌ {\displaystyle...

dinucleotide (NAD+). Metabolites involved in the kynurenine pathway include tryptophan, kynurenine, kynurenic acid, xanthurenic acid, quinolinic acid, and 3-hydroxykynurenine...

Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase found in vertebrates. In humans, TPH2 is primarily expressed in the serotonergic...

Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole...

manufactured tryptophan so that the bacteria would be more efficient. At the same time, they also changed the technique used to purify the tryptophan.: 327–328 ...