• Thumbnail for Tumor necrosis factor
    Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha or TNF-α) is a cytokine and member of the TNF superfamily...
    52 KB (6,302 words) - 07:19, 27 April 2024
  • Thumbnail for Tumor necrosis factor superfamily
    The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers...
    8 KB (316 words) - 22:44, 25 April 2024
  • Thumbnail for TNF receptor superfamily
    The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...
    8 KB (501 words) - 01:30, 27 December 2023
  • Thumbnail for Tumor necrosis factor receptor 1
    Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane...
    19 KB (2,200 words) - 05:21, 25 December 2023
  • pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response. TNF is involved...
    34 KB (3,827 words) - 06:58, 22 April 2024
  • Thumbnail for Tumor necrosis factor receptor 2
    Tumor necrosis factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and CD120b, is one of two membrane...
    12 KB (1,356 words) - 18:10, 27 December 2023
  • Thumbnail for Transforming growth factor beta
    Hussain; Shawana, Summayya (2020). "Dysregulated epidermal growth factor and tumor growth factor-beta receptor signaling through GFAP-ACTA2 protein interaction...
    72 KB (8,680 words) - 21:20, 6 April 2024
  • Thumbnail for Lymphotoxin alpha
    Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the...
    24 KB (2,853 words) - 21:22, 2 April 2024
  • Thumbnail for Fas receptor
    antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans...
    23 KB (2,675 words) - 19:25, 12 November 2023
  • Lymphotoxin is a member of the tumor necrosis factor (TNF) superfamily of cytokines, whose members are responsible for regulating the growth and function...
    12 KB (1,459 words) - 03:14, 30 October 2022
  • Thumbnail for TNF receptor associated periodic syndrome
    syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals...
    8 KB (677 words) - 02:55, 1 December 2023
  • Thumbnail for TRADD
    Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene. TRADD is an adaptor protein...
    16 KB (1,974 words) - 06:12, 25 December 2023
  • Thumbnail for B-cell activating factor
    B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans...
    25 KB (3,095 words) - 14:05, 12 March 2024
  • Thumbnail for RANKL
    Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
    28 KB (3,372 words) - 21:06, 8 March 2024
  • Thumbnail for ADAM17
    disintegrin and metalloprotease 17 (ADAM17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM...
    19 KB (2,383 words) - 14:54, 19 March 2024
  • Thumbnail for CD137
    CD137, a member of the tumor necrosis factor (TNF) receptor family, is a type 1 transmembrane protein, expressed on surfaces of leukocytes and non-immune...
    19 KB (2,216 words) - 01:18, 29 March 2024
  • lipopolysaccharide is thought to increase lymphocyte activity and boosts tumor necrosis factor (TNF). Tsung and Norton in Surgical Oncology reported that the active...
    20 KB (2,297 words) - 16:44, 19 April 2024
  • two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2)....
    4 KB (337 words) - 01:41, 3 December 2023
  • Thumbnail for Lymphotoxin beta receptor
    a member of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of...
    12 KB (1,508 words) - 17:56, 19 August 2022
  • CD40. Tumor necrosis factors Inoue J, Ishida T, Tsukamoto N, Kobayashi N, Naito A, Azuma S, Yamamoto T (January 2000). "Tumor necrosis factor receptor-associated...
    1 KB (136 words) - 07:30, 11 December 2020
  • Thumbnail for Psoriasis
    psoriasis. These genes are on the pathway that upregulate tumor necrosis factor-α and nuclear factor κB, two genes involved in inflammation. The first gene...
    115 KB (12,970 words) - 13:24, 24 April 2024
  • Thumbnail for CD27
    CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint...
    10 KB (1,133 words) - 04:35, 22 December 2023
  • Thumbnail for CD30
    superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but...
    13 KB (1,665 words) - 03:34, 21 December 2023
  • Thumbnail for Sarcoidosis
    mediators, tumor necrosis factor alpha (TNF), interferon gamma, interleukin 2 (IL-2), IL-8, IL-10, IL-12, IL-18, IL-23 and transforming growth factor beta (TGF-β)...
    118 KB (12,895 words) - 05:10, 9 April 2024
  • Thumbnail for TNFRSF12A
    Tumor necrosis factor receptor superfamily member 12A also known as the TWEAK receptor (TWEAKR) is a protein that in humans is encoded by the TNFRSF12A...
    19 KB (2,216 words) - 11:38, 4 January 2024
  • Thumbnail for Bruce Beutler
    tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor...
    112 KB (12,100 words) - 19:34, 23 January 2024
  • Thumbnail for Transmembrane activator and CAML interactor
    Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in...
    13 KB (1,629 words) - 22:42, 25 April 2024
  • Thumbnail for TRAIL
    designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10). In humans, the gene that encodes...
    11 KB (1,335 words) - 11:31, 25 August 2023
  • Thumbnail for TNFRSF18
    Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as glucocorticoid-induced TNFR-related protein (GITR) or CD357. GITR is encoded...
    19 KB (2,117 words) - 05:46, 27 April 2024
  • Thumbnail for Helicobacter pylori
    induce inflammation and locally high levels of tumor necrosis factor (TNF), (also known as tumor necrosis factor alpha (TNFα) and/or interleukin 6 (IL-6)....
    145 KB (16,255 words) - 17:11, 22 April 2024