• Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C-terminus is not removed in post-translational...
    21 KB (2,423 words) - 01:24, 21 April 2024
  • Thumbnail for Collagen, type IV, alpha 1
    is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of the type IV collagen and plays a role in angiogenesis. Mutations in the...
    19 KB (2,457 words) - 07:55, 3 December 2023
  • Thumbnail for Collagen, type IV, alpha 5
    Collagen alpha-5(IV) chain is a protein that in humans is encoded by the COL4A5 gene. This gene encodes one of the six subunits of type IV collagen, the...
    9 KB (1,020 words) - 09:17, 31 July 2023
  • Thumbnail for Collagen, type IV, alpha 3
    Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene. Type IV collagen, the major structural component of basement membranes...
    8 KB (1,058 words) - 01:29, 27 March 2024
  • Thumbnail for Collagen, type IV, alpha 4
    Collagen alpha-4(IV) chain is a protein that in humans is encoded by the COL4A4 gene. This gene encodes one of the six subunits of type IV collagen, the...
    7 KB (946 words) - 21:12, 21 November 2023
  • Thumbnail for Collagen, type IV, alpha 2
    Collagen alpha-2(IV) chain is a protein that in humans is encoded by the COL4A2 gene. This gene encodes one of the six subunits of type IV collagen, the...
    8 KB (1,006 words) - 01:29, 27 March 2024
  • Thumbnail for Alport syndrome
    defect in type IV collagen—a structural material that is needed for the normal function of different parts of the body. Since type IV collagen is found...
    23 KB (2,441 words) - 09:55, 5 May 2024
  • Thumbnail for Collagen, type IV, alpha 6
    Collagen alpha-6(IV) chain is a protein that in humans is encoded by the COL4A6 gene. This gene encodes one of the six subunits of type IV collagen, the...
    8 KB (1,033 words) - 09:17, 31 July 2023
  • Thumbnail for Type IV collagen C4 domain
    type IV collagen C4 domain (or collagen IV NC1 domain) is a duplicated domain present at the C-terminus of type IV collagens. Each type IV collagen contains...
    3 KB (381 words) - 04:10, 11 December 2023
  • Collagenase IV may refer to one of two enzymes: Gelatinase A Gelatinase B This disambiguation page lists articles associated with the title Collagenase IV. If...
    102 bytes (45 words) - 03:16, 28 December 2019
  • Thumbnail for Collagen, type III, alpha 1
    III collagen. Formally, the monomers are called collagen type III, alpha-1 chain and in humans are encoded by the COL3A1 gene. Type III collagen is one...
    29 KB (3,480 words) - 17:49, 26 January 2024
  • Thumbnail for Collagen
    Associated Collagens with Interrupted Triple Helices) (Type IX, XII, XIV, XIX, XXI) Short chain (Type VIII, X) Basement membrane (Type IV) Multiplexin...
    64 KB (6,885 words) - 12:34, 4 May 2024
  • Thumbnail for Goodpasture syndrome
    and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture's antigen. Goodpasture...
    14 KB (1,428 words) - 23:54, 3 March 2024
  • cells of the epidermis, and composed of (1) type IV collagen, (2) anchoring fibrils made of type VII collagen, and (3) dermal microfibrils. Basal lamina...
    793 bytes (88 words) - 01:32, 23 June 2017
  • Thumbnail for Collagen, type I, alpha 1
    Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the COL1A1 gene. COL1A1 encodes the major component...
    13 KB (1,792 words) - 08:24, 26 March 2024
  • Thumbnail for Osteogenesis imperfecta
    problem with connective tissue due to a lack of, or poorly formed, type I collagen.: 1513  In more than 90% of cases, OI occurs due to mutations in the...
    150 KB (15,363 words) - 22:39, 18 April 2024
  • Thumbnail for Glomerular basement membrane
    damage to the basement membrane by antibodies to alpha 3 NC1 domain of type IV collagen. Nephrotic syndrome is a change in the structure of the glomerular...
    5 KB (382 words) - 17:45, 21 June 2023
  • Type IV hypersensitivity, in the Gell and Coombs classification of allergic reactions, often called delayed-type hypersensitivity, is a type of hypersensitivity...
    7 KB (508 words) - 10:59, 15 March 2024
  • Collagen VI (ColVI) is a type of collagen primarily associated with the extracellular matrix of skeletal muscle. ColVI maintains regularity in muscle...
    19 KB (2,434 words) - 18:37, 24 September 2023
  • Thumbnail for Samoyed dog
    defect in the structure of the type-IV collagen fibrils of the glomerular basement membrane. As a consequence, the collagen fibrils of the glomerular basement...
    23 KB (2,619 words) - 16:40, 9 May 2024
  • Thumbnail for Collagen, type VII, alpha 1
    gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the...
    20 KB (2,218 words) - 16:07, 5 April 2024
  • algorithm Type IV collagen, a class of collagen Type-4 hypersensitivity, a class of Hypersensitivity reactions that involves T-cells IEC Type IV, one of...
    1 KB (194 words) - 01:26, 17 September 2023
  • Thumbnail for Tendon
    type II collagen in the cartilaginous zones, type III collagen in the reticulin fibres of the vascular walls, type IX collagen, type IV collagen in the...
    45 KB (5,121 words) - 23:41, 29 March 2024
  • abnormalities, hearing loss, and joint problems. Alport syndrome – defects in collagen (type IV), found in the renal basement membrane, inner ear and eyes, leading...
    12 KB (1,186 words) - 05:04, 25 February 2024
  • Thumbnail for Sponge
    Sponge (section Cell types)
    fibers that reinforce the mesohyl of all demosponges is similar to "type IV" collagen. The analyses described above concluded that sponges are closest to...
    125 KB (12,918 words) - 07:09, 10 May 2024
  • suggesting genetic predisposition within the family, that encodes type IV collagen α1 chain has shown to be associated with and present in patients with...
    18 KB (2,157 words) - 17:26, 15 January 2024
  • Thumbnail for Implantation (embryology)
    The collagenases digest types I, II, III, VII and X collagen. The gelatinases exist in two forms; one digesting Type-IV collagen and one digesting gelatin...
    51 KB (5,851 words) - 05:16, 2 May 2024
  • Thumbnail for Renal corpuscle
    podocyte processes. The lamina densa is the central layer consisting of type IV collagen and laminin. This layer acts as a selective macromolecular filter,...
    5 KB (579 words) - 17:38, 31 December 2023
  • Thumbnail for Rapidly progressive glomerulonephritis
    is characterized by the presence of autoantibodies directed against type IV collagen (specifically, the noncollagenous region of its α3 chain) in the glomerular...
    11 KB (1,047 words) - 17:14, 31 December 2023
  • Thumbnail for Collagen, type VI, alpha 2
    Collagen alpha-2(VI) chain is a protein that in humans is encoded by the COL6A2 gene. This gene encodes one of the three alpha chains of type VI collagen...
    10 KB (1,047 words) - 17:50, 26 January 2024