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DeutschMethyl acetate hydrolase
| Methyl acetate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Collage of methyl acetate hydrolases from various bacterium, from clockwise: Gordonia sp., Nocardioides perillae, Rhodospira trueperi, Calidifontibacter indicus. | |||||||||
| Identifiers | |||||||||
| EC no. | 3.1.1.114 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Methyl acetate hydrolase, known also as methylacetate acetohydrolase is a hydrolase enzyme that utilizes H2O to carry out the hydrolysis of methyl acetate (CH3COOCH3), a weakly lipophillic and polar compound used often as a solvent. In the species Gordonia sp. (strain TY-5), the enzyme is encoded by gene acMB.[1] The enzyme catalyzes the following reaction,
- methyl acetate + H2O = methanol + acetate + H+
The enzyme is involved in two major pathways, the butanoate metabolism pathway and the catabolic degradation pathway of propanol.[2][3][4]
References
[edit]- ^ Kotani T, Yurimoto H, Kato N, Sakai Y (February 2007). "Novel Acetone Metabolism in a Propane-Utilizing Bacterium, Gordonia sp. Strain TY-5". Journal of Bacteriology. 189 (3). NIH: 886–893. doi:10.1128/JB.01054-06. PMC 1797311. PMID 17071761.
- ^ "ENZYME entry: EC 3.1.1.114". Expasy. Database. 2025. Retrieved 26 April 2025.
- ^ "Information on EC 3.1.1.114 - methyl acetate hydrolase". Brenda. Database. 2025. Retrieved 27 April 2025.
- ^ "IUBMB Enzyme Nomenclature EC 3.1.1.114". Queen Mary University, London. 2025. Retrieved 27 April 2025.