OR4E2

OR4E2
Identifiers
Aliases	OR4E2, OR14-42, olfactory receptor family 4 subfamily E member 2, olfactory receptor family 4 subfamily E member 2 (gene/pseudogene)
External IDs	MGI: 3031343 HomoloGene: 41378 GeneCards: OR4E2
Gene location (Human)
Chr.	Chromosome 14 (human)
End	21,667,642 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	52,690,031 bp
RNA expression pattern
	Top expressed in
	renal cortex; ; blood; ; urinary bladder;
	Top expressed in
	Jacobson's organ; ; spermatid; ; respiratory epithelium; ; olfactory epithelium; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity; copper ion binding; odorant binding;
Cellular component	membrane; plasma membrane; integral component of membrane; integral component of plasma membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	26686
	57271
	ENSG00000221977
	ENSMUSG00000035626
	Q8NGC2
	Q7TQQ0
	NM_001001912
	NM_020514
	NP_001001912; NP_001001912
	NP_065260
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 4E2 is a protein that in humans is encoded by the OR4E2 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000221977 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035626 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR4E2 olfactory receptor, family 4, subfamily E, member 2".

External links[edit]

OR4E2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000221977 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035626 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR4E2 olfactory receptor, family 4, subfamily E, member 2".

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OR4E2

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