Olfactomedin 2

OLFM2
Identifiers
Aliases	OLFM2, NOE2, NOELIN2, NOELIN2_V1, OlfC, olfactomedin 2
External IDs	OMIM: 617492 MGI: 3045350 HomoloGene: 14380 GeneCards: OLFM2
Gene location (Human)
Chr.	Chromosome 19 (human)
End	9,936,515 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	20,657,645 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; cingulate gyrus; ; Brodmann area 9; ; prefrontal cortex; ; amygdala; ; caudate nucleus; ; nucleus accumbens; ; hypothalamus; ; skin of abdomen; ; putamen;
	Top expressed in
	visual cortex; ; superior frontal gyrus; ; habenula; ; dorsomedial hypothalamic nucleus; ; primary motor cortex; ; prefrontal cortex; ; cingulate gyrus; ; piriform cortex; ; neural tube; ; dorsal tegmental nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; synaptic membrane; extracellular region; cell junction; AMPA glutamate receptor complex; synapse; membrane; nucleus; nucleoplasm; glutamatergic synapse; extrinsic component of synaptic membrane;
Biological process	positive regulation of smooth muscle cell differentiation; locomotory behavior; visual perception; protein secretion; regulation of vascular associated smooth muscle cell dedifferentiation;
	Sources:Amigo / QuickGO
Orthologs
	93145
	244723
	ENSG00000105088
	ENSMUSG00000032172
	O95897
	Q8BM13
	NM_058164; NM_001304347; NM_001304348
	NM_173777; NM_001357635; NM_001357639
	NP_001291276; NP_001291277; NP_477512
	NP_776138; NP_001344564; NP_001344568
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactomedin 2, also known as noelin 2, is a protein that in humans is encoded by the OLFM2 gene.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105088 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032172 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: OLFM2 olfactomedin 2". Ncbi.nlm.nih.gov. Retrieved 9 November 2017.

Further reading[edit]

Funayama T, Mashima Y, Ohtake Y, et al. (2007). "SNPs and interaction analyses of noelin 2, myocilin, and optineurin genes in Japanese patients with open-angle glaucoma". Invest. Ophthalmol. Vis. Sci. 47 (12): 5368–75. doi:10.1167/iovs.06-0196. PMID 17122126.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mukhopadhyay A, Talukdar S, Bhattacharjee A, Ray K (2004). "Bioinformatic approaches for identification and characterization of olfactomedin related genes with a potential role in pathogenesis of ocular disorders". Mol. Vis. 10: 304–14. PMID 15123989.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
Tomarev SI, Wistow G, Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44 (6): 2588–96. doi:10.1167/iovs.02-1099. PMID 12766061.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105088 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032172 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OLFM2 olfactomedin 2". Ncbi.nlm.nih.gov. Retrieved 9 November 2017.

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