Syndrome Cause cardiac signs and symptoms Other symptoms or organs affected Notes 1q21.1 deletion syndrome genetic (Chromosome 1 ) Cardiovascular anomalies are present in 30% of the cases (for example anomalous origin of the coronary artery in "Class II-deletion") TAR syndrome Neuropsychiatric Craniofacial abnormalities Eye Kidney DiGeorge syndrome genetic (Chromosome 22 ) commonly interrupted aortic arch , truncus arteriosus and tetralogy of Fallot Craniofacial Thymic aplasia Cleft palate Hypocalcemia/hypoparathyroidism Acute coronary syndrome Commonly associated with three clinical manifestations: ST elevation myocardial infarction (STEMI, 30%), non ST elevation myocardial infarction (NSTEMI, 25%), or unstable angina (38%) Blockage of a coronary artery Adams–Nance syndrome maybe disturbance in glycine metabolism persistent tachycardia , paroxymal hypertension Alagille syndrome genetic (Autosomal dominant inheritance: loss of function mutations in either JAG1 or NOTCH2 ) Congenital heart problems e.g. pulmonary artery stenosis (common), Tetralogy of Fallot , overriding aorta , ventricular septal defect ; and right ventricular hypertrophy . Liver (jaundice , pruritus , hepatosplenomegaly , acholia , xanthoma ) Andersen–Tawil syndrome This condition affects the QT interval (in blue) Antley–Bixler syndrome Barth syndrome Brugada syndrome Cantú syndrome genetic (Chromosome 12 , autosomal dominant ) Cardiac syndrome X Cardiorenal syndrome Kidney Cat eye syndrome CHARGE syndrome Coffin–Lowry syndrome genetic (RPS6KA3 gene mutation, Chromosome X ) Costello syndrome Down syndrome genetic (Chromosome 21 ) Dressler syndrome autoimmune inflammatory reaction secondary to MI . Edwards syndrome genetic (Chromosome 18 ) Eisenmenger's syndrome Ellis–van Creveld syndrome Emanuel syndrome HEC syndrome Heyde's syndrome Ho–Kaufman–Mcalister syndrome Holt–Oram syndrome ASD , and a first degree heart block. Hypoplastic left heart syndrome Jacobsen syndrome genetic (Chromosome 11q deletion) Jaffe–Campanacci syndrome Jervell and Lange-Nielsen syndrome genetic (autosomal recessive ) a type of long QT syndrome Kabuki syndrome Kearns–Sayre syndrome Long QT syndrome Lutembacher's syndrome Malpuech facial clefting syndrome Marden–Walker syndrome Marfan syndrome McKusick–Kaufman syndrome McLeod syndrome Noonan syndrome Noonan syndrome with multiple lentigines Ortner's syndrome Bouveret Hoffmann syndrome another name for "Paroxysmal tachycardia " Patau syndrome genetic (Chromosome 13 ) Pre-excitation syndrome Romano–Ward syndrome Scimitar syndrome Shone's syndrome Short QT syndrome Sick sinus syndrome Taussig–Bing syndrome double outlet right ventricle (DORV) and subpulmonic VSD . a cyanotic congenital heart defect Timothy syndrome Townes–Brocks syndrome Triploid syndrome Turner syndrome VACTERL syndrome Wellens' syndrome Williams syndrome Wolff–Parkinson–White syndrome A Delta wave often seen in an affected individual Zunich–Kaye syndrome Lown–Ganong–Levine syndrome