Zinc finger protein 674

ZNF674
Identifiers
Aliases	ZNF674, MRX92, ZNF673B, zinc finger protein 674
External IDs	OMIM: 300573 HomoloGene: 87837 GeneCards: ZNF674
Gene location (Human)
Chr.	X chromosome (human)
End	46,545,457 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ganglionic eminence; ; stromal cell of endometrium; ; islet of Langerhans; ; monocyte; ; gallbladder; ; gastrocnemius muscle; ; smooth muscle tissue; ; right lobe of liver; ; prefrontal cortex;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	641339
	n/a
	ENSG00000251192
	n/a
	Q2M3X9
	n/a
	NM_001039891; NM_001146291; NM_001190417
	n/a
	NP_001034980; NP_001139763; NP_001177346
	n/a
	Wikidata
View/Edit Human

Zinc finger protein 674 is a protein that in humans is encoded by the ZNF674 gene. ^[3]

Function[edit]

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000251192 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 674". Retrieved 2016-03-02.